| Autor: |
Ignace De Decker, Liesl De Graeve, Henk Hoeksema, Stan Monstrey, Jozef Verbelen, Petra De Coninck, Els Vanlerberghe, Karel E. Y. Claes |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Acta chirurgica Belgica. 122(4) |
| ISSN: |
0001-5458 |
| Popis: |
Early surgical debridement of the deep second and third-degree burns is still the standard of care (SOC) to prepare the wound bed for skin grafting. However, this technique has some drawbacks that explain the growing interest in enzymatic debridement as an alternative. In this article, we provide a historic overview as well as the current state-of-the-art and future prospective of this type of non-surgical debridement.A narrative review of the available literature was conducted using a systematic search.A total of 32 articles were included. The only enzyme mixture still used nowadays for burn eschar removal is bromelain-based. There is increasing evidence that this type of enzymatic debridement is a powerful tool to selectively remove the eschar in deep burns, thereby reducing the need for autologous skin grafting compared to surgical SOC. Moreover, off-label use of enzymatic debridement with NexoBridThere is increasing evidence that bedside administered NexoBrid |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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