Societal reintegration after liver transplantation: findings in alcohol-related and non-alcohol-related transplant recipients
| Autor: | Edmund Q. Sanchez, Linda W. Jennings, Terianne Cowling, Srinath Chinnakotla, Robert M. Goldstein, Marlon F. Levy, Goran B. Klintmalm |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Adult
Employment Graft Rejection Liver Cirrhosis Male Alcoholic liver disease medicine.medical_specialty medicine.medical_treatment Disease Liver transplantation Risk Assessment Severity of Illness Index Statistics Nonparametric Liver disease Quality of life Liver Cirrhosis Alcoholic Predictive Value of Tests Reference Values Surveys and Questionnaires Severity of illness medicine Humans Interpersonal Relations Intensive care medicine Survival rate Aged Probability business.industry Graft Survival Original Articles Middle Aged medicine.disease Prognosis Liver Transplantation Transplantation Treatment Outcome Case-Control Studies Quality of Life Surgery Female business |
| Zdroj: | Annals of surgery. 239(1) |
| ISSN: | 0003-4932 |
| Popis: | Enabling patients to reenter society as active and productive members is a key goal of liver transplantation (OLTX). Today, OLTX sustains favorable rates of patient survival: 87.0% at 1 year, 80.9% at 3 years, and 75.1% at 5 years post-OLTX (recipients of cadaveric donors).1 Nevertheless, its use remains limited by the scarcity of donor organs. In light of this organ shortage, the transplant community is increasingly called upon to justify its practices and show the impact of transplantation beyond survival. One controversial group of transplant candidates is those suffering from alcohol-induced liver disease. Today, alcoholic liver disease (ALD) ranks as the second leading cause of OLTX among adults within the United States, with the proportion of transplanted recipients having increased from 13.2% in 1988 to 26.9% in 1995.2 Despite survival rate similarity between alcohol-related and non–alcohol-related OLTX recipients,3–6 the general public seems less willing to allocate donor livers to those with alcohol-related liver disease than to those whose disease is unrelated to alcohol use.7,8 Although liver transplantation is well recognized as a lifesaving procedure, questions remain regarding its comprehensive long-term effects on transplant recipients. Various studies have measured post-OLTX quality of life by examining specific domains among its recipient populations, primarily employment, physical and cognitive abilities, emotional and social well-being, role limitations, self-image, and health perceptions.9–13 Emphasis has typically focused on the abilities and limitations of liver recipients following transplant, rather than on what the recipients actually do during the course of their daily lives. Given the high costs of liver transplantation,14 investigation into the life experiences of OLTX recipients may provide a better understanding of the value of this procedure and the overall long-term effects of patient survival upon society. The purpose of this study was to describe and qualify liver transplant recipients’ societal reintegration post-OLTX and, further, to compare the degree of societal reintegration between individuals transplanted for alcohol-related and non–alcohol-related liver disease. |
| Databáze: | OpenAIRE |
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