The usage of a lactobacilli probiotic in the non-surgical therapy of peri-implantitis: A randomized pilot study
| Autor: | Marc Quirynen, Wim Teughels, Martine Pauwels, Isabelle Laleman |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Peri-implantitis
Saliva Technology Dentistry Pilot Projects 02 engineering and technology law.invention Probiotic PHOTODYNAMIC THERAPY DOUBLE-BLIND 0302 clinical medicine Engineering law gingival bleeding on probing OUTCOMES biology REUTERI-CONTAINING TABLETS Oral Surgery medicine.symptom Life Sciences & Biomedicine debridement peri-implantitis dental plaque LOZENGES 0206 medical engineering Bleeding on probing Dental plaque Placebo Lactobacilli reuteri 03 medical and health sciences Double-Blind Method Dentistry Oral Surgery & Medicine medicine Humans Engineering Biomedical therapy CHRONIC PERIODONTITIS Science & Technology business.industry Probiotics 030206 dentistry LOCAL-DRUG DELIVERY medicine.disease biology.organism_classification Peri-Implantitis 020601 biomedical engineering Lactobacillus reuteri Lactobacillus probiotics Implant MUCOSITIS business ANTIINFECTIVE THERAPY |
| Popis: | OBJECTIVES: Examine the clinical and microbiological benefits of a dual-strain Lactobacillus reuteri probiotic on the non-surgical therapy of initial peri-implantitis. MATERIALS AND METHODS: This randomized, double-blind study targeted patients with initial peri-implantitis, that is peri-implantitis with a maximum mean probing pocket depth of 6 mm and maximum 3 mm bone loss compared with loading. A full-mouth prophylaxis was performed and the peri-implantitis sites were debrided. Subsequently, local application of the study drops was carried out at the peri-implantitis sites and the study lozenges were handed out. The patients in the probiotic group received drops and lozenges containing L. reuteri (ATCC PTA 5289 & DSM 17938), those in the control group received placebo products. At the implant level the measurements of interest were bleeding, probing pocket depth and plaque. Full-mouth bleeding and plaque scores were also recorded. Microbiological samples were taken from the tongue, saliva and subgingivally around the implants. RESULTS: All clinical parameters were significantly decreased after 12 and 24 weeks. At the implant level the only statistically significant difference was a greater decrease in plaque levels in the probiotic versus the control group (p = .002 at 24 weeks). At the full-mouth level, the only intergroup difference was the greater decrease in full-mouth bleeding on probing sites in the probiotic group compared with the control group (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|