Are P Wave and QT Dispersions Related to Severe Peripheral Artery Disease?
| Autor: | Efe Edem, Hasan Reyhanoglu |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty Arterial disease Context (language use) Coronary Artery Disease Constriction Pathologic Disease 030204 cardiovascular system & hematology Coronary Angiography Sensitivity and Specificity Severity of Illness Index Coronary artery disease Electrocardiography Peripheral Arterial Disease 03 medical and health sciences 0302 clinical medicine Clinical Research Predictive Value of Tests Risk Factors Internal medicine medicine Humans 030212 general & internal medicine Aged Peripheral angiography Peripheral Vascular Diseases Receiver operating characteristic business.industry General Medicine Middle Aged medicine.disease Stenosis ROC Curve Assessment methods Cardiology Female business Biomarkers |
| Zdroj: | Medical Science Monitor : International Medical Journal of Experimental and Clinical Research |
| ISSN: | 1643-3750 |
| DOI: | 10.12659/msm.910107 |
| Popis: | Background The aim of this study was to evaluate the relationship between P wave and QT dispersions (PWD and QTD) during the course of severe peripheral artery disease (PAD). Material/Methods We recruited 163 patients who underwent peripheral angiography (PA) between August 2011 and March 2017, and they were divided into 2 groups according to the severity of PAD on PA. PWD and QTD were investigated using 12-lead electrocardiograms. Group One consisted of patients diagnosed with 35 msn predicted a peripheral artery stenosis of ≥70% with a sensitivity of 88.89% and a specificity of 85.37% (+LR: 6.07, −LR: 0.13). Moreover, QTD was significantly higher in Group Two (AUC: 0.884749; 95% CI: 0.825489 to 0.929391; p75 msn predicted a peripheral artery stenosis of ≥70% with a sensitivity of 76.54% and a specificity of 85.37% (+LR: 5.23, −LR: 0.27). Comparison of ROC curves showed no difference in terms of predicting peripheral artery stenosis of ≥70% between PWD and QTD (p=0.3308). Conclusions Interpreting PWD and QTD offers a non-invasive and cost-effective assessment method for detecting patients at high risk for coronary artery disease in the context of severe PAD. |
| Databáze: | OpenAIRE |
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