MRI and 18F-FDG-PET/CT in a rare case of early (precursor) B-lymphoblastic leukaemia with bone involvement as initial manifestation

Autor:	Maurizio Cogoni, Gianpaolo Di Rosa, Natale Quartuccio, Vincenzo La Delfa, Angelina Cistaro
Rok vydání:	2015
Předmět:	musculoskeletal diseases medicine.medical_specialty Sternum Bone Neoplasms 02 engineering and technology Lumbar vertebrae Multimodal Imaging 03 medical and health sciences 0302 clinical medicine Fluorodeoxyglucose F18 Positron Emission Tomography Computed Tomography Precursor B-Cell Lymphoblastic Leukemia-Lymphoma Biopsy medicine Humans Radiology Nuclear Medicine and imaging medicine.diagnostic_test business.industry Magnetic resonance imaging General Medicine 021001 nanoscience & nanotechnology Magnetic Resonance Imaging medicine.anatomical_structure Positron emission tomography 030220 oncology & carcinogenesis Child Preschool Lymphoblastic leukaemia Fdg pet ct Female Radiology Bone marrow Radiopharmaceuticals 0210 nano-technology Nuclear medicine business
Zdroj:	Nuclear medicine review. CentralEastern Europe. 20(1)
ISSN:	1644-4345
Popis:	A 4-year old girl presenting gait difficulty was referred for spine X-ray and Magnetic Resonance Imaging (MRI). MRI showed several diffuse hypointense signals in sacral and lumbar vertebrae. In order to exclude a possible lymphoproliferative disease a 18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG-PET/CT) was requested. The PET/CT scan confirmed the MRI findings and demonstrated additional findings in the sternum. Therefore, a bone marrow biopsy was performed and a diagnosis of acute lymphoblastic leukaemia - early B type was made.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fcf5d166deeb2322c1c06e7d39d2cf6 https://pubmed.ncbi.nlm.nih.gov/28218349 Zobrazit plný text záznamu