Localization of the hypothetical protein Cpn0797 in the cytoplasm of Chlamydia pneumoniae-infected host cells
| Autor: | Guangming Zhong, Feng Dong, Ding Chen, Youmin Zhong, Rhonda Flores, Jianhua Luo, Zhongming Wu |
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| Rok vydání: | 2006 |
| Předmět: |
Antigens
Bacterial Cytoplasm Host cell cytosol Cellular Microbiology: Pathogen-Host Cell Molecular Interactions biology Immunology Hypothetical protein Chlamydophila pneumoniae medicine.disease_cause Microbiology Fusion protein Open reading frame Cytosol Open Reading Frames Infectious Diseases medicine biology.protein Humans Parasitology Antibody HeLa Cells |
| Zdroj: | Infection and immunity. 74(11) |
| ISSN: | 0019-9567 |
| Popis: | Using antibodies raised with chlamydial fusion proteins, we have localized a protein encoded by the hypothetical open reading frame Cpn0797 in the cytoplasm of Chlamydia pneumoniae -infected host cells. The anti-Cpn0797 antibodies specifically recognized Cpn0797 protein without cross-reacting with either CPAFcp or Cpn0796, the only two proteins known to be secreted into the host cell cytosol by C. pneumoniae organisms. Thus, Cpn0797 represents the third C. pneumoniae protein secreted into the host cell cytosol experimentally identified so far. |
| Databáze: | OpenAIRE |
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