Youngest case of ductal carcinoma in situ arising within a benign phyllodes tumour: A case report
Autor: | Vummiti Muralikrishnan, Sharat Chopra, Maurizio Brotto |
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Rok vydání: | 2016 |
Předmět: |
In situ
Pathology medicine.medical_specialty business.industry Young age Ductal carcinoma in situ Case Report 030230 surgery Ductal carcinoma medicine.disease Fibroadenoma body regions 03 medical and health sciences 0302 clinical medicine Benign 030220 oncology & carcinogenesis medicine Surgery business skin and connective tissue diseases Phyllodes tumour |
Zdroj: | International Journal of Surgery Case Reports |
ISSN: | 2210-2612 |
DOI: | 10.1016/j.ijscr.2016.04.053 |
Popis: | Highlights • Phyllodes tumour is a rare type of breast tumour, accounting for less than 1% of benign and malignant breast tumours. • Phyllodes tumour is classified pathologically as benign, borderline or malignant. • Phyllodes tumour with ductal carcinoma in situ can exist as separate foci or arise from within the tumour. • Phyllodes tumour usually presents in late 50s but has never been reported in a 23-year-old nulliparous woman. Introduction Phyllodes tumour (PT) is a rare tumour of the female breast. The tumour clinically and radiologically mimics the features of a fibroadenoma. Ductal carcinoma in situ (DCIS) in the epithelial component of PT is a very rare finding. Presentation of case We present youngest ever case of a 23-year-old nulliparous woman with high-grade ductal carcinoma in situ arising within a benign phyllodes tumor. Macroscopically, it is a homogeneous tumour with solid components. Microscopically, it features typical leaf-like pattern with hypercellular stroma with high-grade ductal carcinoma in situ. Discussion To date, eight such rare cases of benign phyllodes tumour with ductal carcinoma in situ have been documented. We report the youngest case known in literature so far. Conclusion As this is a very rare presentation, it poses several challenges in regard to both management and follow-up. |
Databáze: | OpenAIRE |
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