Youngest case of ductal carcinoma in situ arising within a benign phyllodes tumour: A case report

Autor: Vummiti Muralikrishnan, Sharat Chopra, Maurizio Brotto
Rok vydání: 2016
Předmět:
Zdroj: International Journal of Surgery Case Reports
ISSN: 2210-2612
DOI: 10.1016/j.ijscr.2016.04.053
Popis: Highlights • Phyllodes tumour is a rare type of breast tumour, accounting for less than 1% of benign and malignant breast tumours. • Phyllodes tumour is classified pathologically as benign, borderline or malignant. • Phyllodes tumour with ductal carcinoma in situ can exist as separate foci or arise from within the tumour. • Phyllodes tumour usually presents in late 50s but has never been reported in a 23-year-old nulliparous woman.
Introduction Phyllodes tumour (PT) is a rare tumour of the female breast. The tumour clinically and radiologically mimics the features of a fibroadenoma. Ductal carcinoma in situ (DCIS) in the epithelial component of PT is a very rare finding. Presentation of case We present youngest ever case of a 23-year-old nulliparous woman with high-grade ductal carcinoma in situ arising within a benign phyllodes tumor. Macroscopically, it is a homogeneous tumour with solid components. Microscopically, it features typical leaf-like pattern with hypercellular stroma with high-grade ductal carcinoma in situ. Discussion To date, eight such rare cases of benign phyllodes tumour with ductal carcinoma in situ have been documented. We report the youngest case known in literature so far. Conclusion As this is a very rare presentation, it poses several challenges in regard to both management and follow-up.
Databáze: OpenAIRE