Maternal caffeine intake during pregnancy is associated with birth weight but not with gestational length: results from a large prospective observational cohort study
| Autor: | Staffan Nilsson, Jonas Bacelis, Verena Sengpiel, Bo Jacobsson, Margaretha Haugen, Jan Alexander, Jakob Grove, Elisabeth Elind, Helle Margrete Meltzer, Ronny Myhre, Anne-Lise Brantsæter |
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| Rok vydání: | 2013 |
| Předmět: |
Adult
medicine.medical_specialty Birth weight Population Intrauterine growth restriction Cohort Studies Young Adult 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Pregnancy Caffeine medicine Birth Weight Humans 030212 general & internal medicine education Medicine(all) education.field_of_study 030219 obstetrics & reproductive medicine Norway business.industry Obstetrics General Medicine medicine.disease Diet 3. Good health chemistry Premature birth Premature Birth Gestation Small for gestational age Female business |
| Zdroj: | Sengpiel, V, Elind, E, Bacelis, J, Nilsson, S, Grove, J, Myhre, R, Haugen, M, Margrete Meltzer, H, Alexander, J, Jacobsson, B & Brantsæter, A-L 2013, ' Maternal caffeine intake during pregnancy is associated with birth weight but not with gestational length: results from a large prospective observational cohort study ', B M C Medicine, vol. 11, no. 42 . https://doi.org/10.1186/1741-7015-11-42 |
| ISSN: | 1741-7015 |
| DOI: | 10.1186/1741-7015-11-42 |
| Popis: | BACKGROUND: Pregnant women consume caffeine daily. The aim of this study was to examine the association between maternal caffeine intake from different sources and (a) gestational length, particularly the risk for spontaneous preterm delivery (PTD), and (b) birth weight (BW) and the baby being small for gestational age (SGA). METHODS: This study is based on the Norwegian Mother and Child Cohort Study conducted by the Norwegian Institute of Public Health. A total of 59,123 women with uncomplicated pregnancies giving birth to a live singleton were identified. Caffeine intake from different sources was self-reported at gestational weeks 17, 22 and 30. Spontaneous PTD was defined as spontaneous onset of delivery between 22+0 and 36+6 weeks (n = 1,451). As there is no consensus, SGA was defined according to ultrasound-based (Marsal, n = 856), population-based (Skjaerven, n = 4,503) and customized (Gardosi, n = 4,733) growth curves. RESULTS: The main caffeine source was coffee, but tea and chocolate were the main sources in women with low caffeine intake. Median pre-pregnancy caffeine intake was 126 mg/day (IQR 40 to 254), 44 mg/day (13 to 104) at gestational week 17 and 62 mg/day (21 to 130) at gestational week 30. Coffee caffeine, but not caffeine from other sources, was associated with prolonged gestation (8 h/100 mg/day, P |
| Databáze: | OpenAIRE |
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