Functional assessment of coronary artery flow using adenosine stress dual-energy CT: a preliminary study

Autor: Hideyuki Saeki, Kouki Watanabe, Kohei Hosokawa, Hideki Okayama, Teruhito Kido, Hiroshi Higashino, Teruhito Mochizuki, Michinobu Nagao, Akira Kurata
Jazyk: angličtina
Rok vydání: 2010
Předmět:
Male
medicine.medical_specialty
Adenosine
Vasodilator Agents
Myocardial Ischemia
Contrast Media
Pilot Projects
Coronary Angiography
Severity of Illness Index
Iopamidol
Coronary artery disease
Myocardial perfusion imaging
Coronary circulation
Japan
Predictive Value of Tests
Internal medicine
Coronary Circulation
medicine
Humans
Radiology
Nuclear Medicine and imaging
CT coronary angiogram
Cardiac imaging
Aged
Retrospective Studies
Aged
80 and over
Original Paper
medicine.diagnostic_test
business.industry
Coronary artery flow
Coronary Stenosis
Myocardial Perfusion Imaging
Middle Aged
medicine.disease
Coronary arteries
medicine.anatomical_structure
Dual-energy CT
Radiology Nuclear Medicine and imaging
Predictive value of tests
Case-Control Studies
Cardiology
Radiographic Image Interpretation
Computer-Assisted
Female
Cardiology and Cardiovascular Medicine
business
Tomography
X-Ray Computed
medicine.drug
Artery
Zdroj: The International Journal of Cardiovascular Imaging
ISSN: 1875-8312
1569-5794
Popis: We attempted to assess coronary artery flow using adenosine-stress and dual-energy mode with dual-source CT (DE-CT). Data of 18 patients with suspected coronary arteries disease who had undergone cardiac DE-CT were retrospectively analyzed. The patients were divided into two groups: 10 patients who performed adenosine stress CT, and 8 patients who performed rest CT as controls. We reconstructed an iodine map and composite images at 120 kV (120 kV images) using raw data with scan parameters of 100 and 140 kV. We measured mean attenuation in the coronary artery proximal to the distal portion on both the iodine map and 120 kV images. Coronary enhancement ratio (CER) was calculated by dividing mean attenuation in the coronary artery by attenuation in the aortic root, and was used as an estimate of coronary enhancement. Coronary stenosis was identified as a reduction in diameter of >50% on CT angiogram, and myocardial ischemia was diagnosed by adenosine-stress myocardial perfusion scintigraphy. The iodine map showed that CER was significantly lower for ischemic territories (0.76 ± 0.06) or stenosed coronary arteries (0.77 ± 0.06) than for non-ischemic territories (0.95 ± 0.21, P = 0.02) or non-stenosed coronary arteries (1.07 ± 0.33, P
Databáze: OpenAIRE
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