Oncological outcome, functional results and costs after unplanned excision of musculoskeletal soft tissue sarcoma
| Autor: | Michael Montemurro, Maurice Matter, Hannes A. Rüdiger, Igor Letovanec, Laurent Mustaki, Andre D. Durham, Patrick Omoumi, Pietro G. di Summa, Stéphane Cherix, Fabio Becce, Boris Morattel |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Leiomyosarcoma Male medicine.medical_specialty Adolescent Soft Tissue Neoplasms Subgroup analysis Myxosarcoma Resection Sarcoma Synovial Young Adult 03 medical and health sciences 0302 clinical medicine MUSCULOSKELETAL/SOFT TISSUE Humans Medicine In patient Child Aged Retrospective Studies Aged 80 and over 030222 orthopedics business.industry Significant difference Distant recurrence Soft tissue Sarcoma Health Care Costs Liposarcoma Recovery of Function General Medicine Length of Stay Middle Aged medicine.disease Tumor Burden Surgery Survival Rate Treatment Outcome Oncology Surgical Procedures Operative 030220 oncology & carcinogenesis Female Neoplasm Recurrence Local business |
| Zdroj: | European Journal of Surgical Oncology. 46:898-904 |
| ISSN: | 0748-7983 |
| Popis: | Treatment of soft tissue sarcomas (STS) should only be initiated once the diagnosis is fully established. Resection of tumors of unknown nature should be avoided. Nevertheless, specialized centers continue to face numbers of unplanned excisions (UPE) in STS.To compare oncologic and functional outcomes, number of surgeries, length of hospital stay and treatment costs of UPE versus planned excision (PE) in STS.A retrospective single tertiary center study was performed on 201 patients. Survival, local and distant recurrence rates were compared between PE (n = 137) and UPE (n = 64). In a subgroup analysis of 60 patients, functional outcome (MSTS and TESS scores), and socio-economic impact (number of surgeries, length of hospital stay and treatment costs) in "functional planned excision" (fPE) group (n = 30) and "functional unplanned excision" (fUPE) group (n = 29) were compared.There was no significant difference in oncological outcome between PE and UPE. In the subgroup analysis, we found a non-significant difference in functional outcome. Patients in the fUPE had significantly more surgeries (3.5 vs. 1.4; p 0.00001) and costs of their management was 64% higher than fPE (p = 0.048). Hospital stay was longer after fUPE but not statistically significant (18.3 days vs. 11.8 days; p = 0.13).Even though oncological and functional outcomes are comparable after PE and UPE of STS, the number of surgeries, length of hospital stay and treatment costs were higher in patients with UPE. Our data underscore the importance of specialized STS treatment centers including multidisciplinary management. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect