Moderate Exercise Training and Natural Killer Cell Cytotoxic Activity in Breast Cancer Patients
Autor: | O. R. Fagoaga, Sandra L. Nehlsen-Cannarella, David C. Nieman, W. J. Rejeski, J. Suttles, P. M. Ribisl, Dru A. Henson, V. D. Cook |
---|---|
Rok vydání: | 1995 |
Předmět: |
Adult
Cytotoxicity Immunologic medicine.medical_specialty Strength training Lymphocyte medicine.medical_treatment Physiology Breast Neoplasms Physical Therapy Sports Therapy and Rehabilitation Physical exercise Natural killer cell Breast cancer Internal medicine medicine Humans Cytotoxic T cell Aerobic exercise Orthopedics and Sports Medicine Leg strength Exercise Aged Chemotherapy Oncology (nursing) business.industry Rehabilitation Middle Aged medicine.disease Killer Cells Natural medicine.anatomical_structure Endocrinology Oncology Moderate exercise Female business |
Zdroj: | International Journal of Sports Medicine. 16:334-337 |
ISSN: | 1439-3964 0172-4622 |
Popis: | Sixteen female breast cancer patients who had been diagnosed (3.0 +/- 1.2 years previous to the study) and undergone surgery, chemotherapy, and/or radiation treatment were randomly assigned to exercise and nonexercise groups. Pre- and post-study measurements were taken for aerobic performance, leg strength, and concentrations of circulating lymphocyte subsets and natural killer cell cytotoxic activity (NKCA). Exercise training consisted of 60 minutes of supervised weight training and aerobic activity three times each week for eight weeks. Although subjects in the exercise groups demonstrated some modest improvement in the various aerobic and strength tests, NKCA and concentrations of circulating T and NK cells were not significantly altered relative to the nonexercise group. This study suggests that moderate exercise over an eight-week period has no significant effect on the function of in vitro natural killer cells in breast cancer patients. |
Databáze: | OpenAIRE |
Externí odkaz: |