Viral etiology of sporadic cases of parotitis among children in Korea during 2013-2014
| Autor: | Seung Bong Choi, Hye Eun Eom, Ok Young Park, Sun H. Kim, Kisoon Kim, Jae K. Chung, Soon Won Lee, Sung S. Kim, Hae J. Kang |
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| Rok vydání: | 2017 |
| Předmět: |
Male
0301 basic medicine Herpesvirus 4 Human Adolescent viruses 030106 microbiology Buccal swab Mumps virus Real-Time Polymerase Chain Reaction medicine.disease_cause Virus 03 medical and health sciences 0302 clinical medicine Virology Republic of Korea medicine Humans 030212 general & internal medicine Child Mumps biology Coinfection business.industry Incidence (epidemiology) Human bocavirus Infant biology.organism_classification medicine.disease Epstein–Barr virus Infectious Diseases Child Preschool Viruses Female Human herpesvirus 6 business Parotitis |
| Zdroj: | Journal of Medical Virology. 90:61-66 |
| ISSN: | 0146-6615 |
| DOI: | 10.1002/jmv.24935 |
| Popis: | Recent years have seen a high incidence of mumps, which is generally diagnosed based on clinical features, especially parotitis, without laboratory confirmation in Korea. To better understand the epidemiology of mumps in Korean children, we investigated sporadic suspected mumps cases with parotitis. In total, 237 buccal swabs or throat swabs collected from children with parotitis who had been clinically diagnosed with mumps were tested using real-time PCR for the detection of six viruses (Epstein-Barr virus, Human herpesvirus 6, Mumps virus, Human parainfluenza virus-1, -2, -3, Human adenovirus, Human bocavirus). Among 237 parotitis cases, 87 (36.7%) were positive for at least one virus; a single infection was observed in 73 (83.9%) cases, and co-infections were detected in 14 (16.1%) cases. Epstein-Barr virus was most frequent (20.7%), followed by human herpesvirus 6 (8.0%), mumps virus (5.5%), human parainfluenza virus-3 (4.6%), human adenovirus (4.2%), and human bocavirus (0.4%). These data suggested that the sporadic suspected mumps in the children might be related to other respiratory viruses rather than to the mumps virus. Our findings also indicate the limitation of clinical diagnosis without laboratory confirmation for mumps and thus highlight the importance of laboratory testing in suspected mumps cases. |
| Databáze: | OpenAIRE |
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