The influence of ethnicity on disease outcome in patients with chronic hepatitis B infection
| Autor: | Özgür M Koc, Beytullah Yildirim, Ger H. Koek, Geert Robaeys, Dirk Posthouwer, Niel Hens |
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| Přispěvatelé: | RS: NUTRIM - R2 - Liver and digestive health, Med Microbiol, Infect Dis & Infect Prev, Promovendi NTM, MUMC+: DA MMI Staf (9), Interne Geneeskunde, MUMC+: MA Maag Darm Lever (9), OMÜ |
| Rok vydání: | 2018 |
| Předmět: |
Liver Cirrhosis
Male Multivariate analysis Cirrhosis Turkey C INFECTION Turkish Alcohol abuse CHILDREN Liver disease 0302 clinical medicine Belgium Prevalence FIBROSIS Medicine 030212 general & internal medicine PREDICTORS Research Articles Netherlands CHANGING EPIDEMIOLOGY EDUCATION Middle Aged Hepatitis B Infectious Diseases ethnicity Female 030211 gastroenterology & hepatology BURDEN Life Sciences & Biomedicine Research Article Adult medicine.medical_specialty Turkish population Emigrants and Immigrants VIRUS-INFECTION socioeconomic status 03 medical and health sciences Hepatitis B Chronic Virology Internal medicine Humans Science & Technology disease outcome business.industry cirrhosis NATURAL-HISTORY Odds ratio Hepatology medicine.disease PREVENTION Human medicine hepatitis B business |
| Zdroj: | Journal of Medical Virology, 91(4), 623-629. Wiley Journal of medical virology Journal of Medical Virology |
| ISSN: | 0146-6615 |
| Popis: | Since the cultural diversity in Western Europe is growing, this study assessed whether foreign‐born chronic hepatitis B (CHB) patients have more cirrhosis than Dutch‐ or Belgian‐born patients, with a main focus on the Turkish population. Baseline characteristics (eg, socioeconomic status [SES]), biological characteristics, and disease outcome (eg, cirrhosis) were collected for all patients. Between December 2009 and January 2015, 269 CHB patients participated from the outpatient departments of three hospitals in the Netherlands, Belgium, and Turkey. Out of the 269 CHB patients, 210 were foreign‐born and 59 were Dutch‐ or Belgian‐born. Compared with Dutch‐ or Belgian‐born patients, foreign‐born patients had a higher prevalence of low SES (58% vs 31%; P = 0.001) and cirrhosis (27% vs 10%; P = 0.007). Among the Turkish population, there were no significant differences regarding the prevalence of low SES (73% vs 61%; P = 0.170), alcohol abuse (1% vs 5%; P = 0.120), anti‐hepatitis C virus positivity (4% vs 0%; P = 0.344), anti‐hepatitis D virus positivity (1% vs 6%; P = 0.297), and cirrhosis (37% vs 27%; P = 0.262) between patients (n = 102) living in Turkey (local) and Turkish CHB (n = 38) patients living in the Netherlands or Belgium (immigrant). In multivariate analysis, low SES (odds ratio, 5.7; 95% confidence interval, 2.3‐14.5; P Foreign‐born individuals have a higher prevalence of cirrhosis than Dutch‐ or Belgian‐ born individualsThere was a lower socioeconomic status in the foreign‐born individualsNo difference in the prevalence of cirrhosis was seen between the local and immigrant Turkish populationSocioeconomic status and not ethnicity was an independent predictor of cirrhosis |
| Databáze: | OpenAIRE |
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