Incorporation of free fatty acids can explain alterations in the molecular species composition of phosphatidylcholine and phosphatidyethanolamine in human erythrocytes as induced by Plasmodium falciparum
| Autor: | A Simoes, Ben Roelofsen, J Opdenkamp |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Erythrocytes
Plasmodium falciparum Palmitic Acid Phospholipid Palmitic Acids Fatty Acids Nonesterified Host-Parasite Interactions Membrane Lipids chemistry.chemical_compound Phosphatidylcholine medicine Animals Humans Diacylglycerol kinase Phosphatidylethanolamine biology Phosphatidylethanolamines Erythrocyte Membrane Cell Biology Ethanolaminephosphotransferase biology.organism_classification Red blood cell medicine.anatomical_structure Biochemistry chemistry Diacylglycerol Cholinephosphotransferase Phosphatidylcholines Composition (visual arts) Stearic Acids Phosphotransferases |
| Zdroj: | Cell Biology International Reports. 16:533-545 |
| ISSN: | 0309-1651 |
| DOI: | 10.1016/s0309-1651(05)80052-9 |
| Popis: | Summary Phosphatidylcholine (PC) and phosphatidylethanolamine (PE) species composition of human erythrocytes changes upon intraerythrocytic development of Plasmodium falciparum . Though the activity of the phosphotransferases which catalyze the last step of the Kennedy pathway for the synthesis of PC and PE is dependent of the species on diacylglycerol, it appeared that this cannot, by itself, explain the alterations found in PC and PE molecular species composition. When the incorporation of radiolabeled palmitic and stearic acids in PC and PE was studied, it became clear that differences in the incorporation of fatty acids in those phospholipids might be responsible for the observed alterations in their molecular species composition. |
| Databáze: | OpenAIRE |
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