Sickle cell anemia in Brazil: personal, medical and endodontic patterns
| Autor: | Leda Quercia Vieira, Warley Luciano Fonseca Tavares, Antônio Paulino Ribeiro Sobrinho, Hercílio Martelli Júnior, Luciana Carla Neves de Brito, Shirlene Barbosa Pimentel Ferreira, Marco Aurélio Camargo da Rosa |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Male
Blood transfusion Cross-sectional study medicine.medical_treatment Disease Leukocyte Count 0302 clinical medicine Antisickling Agents Hydroxyurea General Materials Science Child education.field_of_study Dental Pulp Diseases Middle Aged Sickle cell anemia Root Canal Therapy Child Preschool Vitamin B Complex Splenectomy Female Brazil Needs Assessment Adult Endodontic therapy medicine.medical_specialty Adolescent Anemia Population Anemia Sickle Cell Endodontics Young Adult 03 medical and health sciences Folic Acid Internal medicine medicine Humans Blood Transfusion Serologic Tests education business.industry 030206 dentistry medicine.disease Surgery Hemoglobinopathies lcsh:RK1-715 Cross-Sectional Studies lcsh:Dentistry business 030215 immunology |
| Zdroj: | Brazilian Oral Research, Vol 30, Iss 1 (2016) Brazilian Oral Research v.30 n.1 2016 Brazilian Oral Research Sociedade Brasileira de Pesquisa Odontológica (SBPqO) instacron:SBPQO Brazilian Oral Research, Volume: 30, Issue: 1, Article number: e60, Published: 20 MAY 2016 |
| ISSN: | 1807-3107 |
| Popis: | Sickle cell anemia (SCA) is the most prevalent genetic disease worldwide. Recurrent vaso-occlusive infarcts predispose SCA patients to infections, which are the primary causes of morbidly and mortality. This study aimed to evaluate the relationship between SCA and endodontic diseases. Personal information, medical data (hematological indices, virologic testing, blood transfusions, medications received, splenectomy) and information on the need for endodontic treatment were obtained from SCA patients who were registered and followed up by the Fundação Hemominas, Minas Gerais, Brazil.These data were compared with the need for root canal treatment in SCA patients. One hundred eight patients comprised the studied population, and the rate of the need for endodontic therapy was 10.2%. Among the medical data, a significant difference was observed for eosinophil (p = 0.045) counts and atypical lymphocyte counts (p = 0.036) when the groups (with and without the need for endodontic treatment) were compared. Statistical relevance was observed when comparing the patients with and without the need for root canal therapy concerned eosinophil counts and atypical lymphocyte counts. The differences in statistical medical data, observed between the groups suggest that both parameters are naturally connected to the stimulation of the immune system that can occur in the presence of root canal infections and that can be harmful to SCA individuals. |
| Databáze: | OpenAIRE |
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