Procalcitonin in the diagnosis of inflammation in intensive care units
| Autor: | Aldo Luzzani, Anna Ferrari, Paolo Rizzotti, Piersandro Sette, Romolo M. Dorizzi, Enrico Polati |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Adult
Calcitonin Male medicine.medical_specialty Calcitonin Gene-Related Peptide Clinical Biochemistry Inflammation Procalcitonin Sepsis procalcitonin intensive care sepsis Internal medicine Intensive care medicine Humans Cutoff Protein Precursors Aged Septic shock business.industry Critically ill General Medicine Plasma levels Middle Aged medicine.disease Shock Septic Systemic Inflammatory Response Syndrome Surgery Intensive Care Units ROC Curve Female medicine.symptom business |
| Zdroj: | Clinical Biochemistry. 39:1138-1143 |
| ISSN: | 0009-9120 |
| DOI: | 10.1016/j.clinbiochem.2006.08.011 |
| Popis: | Objectives: To assess the effectiveness of different procalcitonin cutoff values to distinguish non-infected (negative + SIRS) from infected (sepsis + severe sepsis + septic shock) medical and surgical patients. Design and methods: PCT plasma concentration was measured using an automated chemiluminescence analyzer in 1013 samples collected in 103 patients within 24 h of admission in ICU and daily during the ICU stay. We compared PCT levels in medical and surgical patients. We also compared PCT plasma levels in non-infected versus infected patients and in SIRS versus infected patients both in medical and in surgical groups. Results: Median values of PCT plasma concentrations were significantly higher in infected than in non-infected groups, both in medical (3.18 vs. 0.45 μg/L) (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect