Long-term survival after enucleation of a giant esophageal gastrointestinal stromal tumor
| Autor: | Hao Wu, Gang Hui, Yuancai Xie, Hai Zhang, Xuxing Peng, Baokun Chen, Zhimin Mu, Jixian Liu, Da Wu, Yiwang Ye |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors Esophageal Neoplasms Gastrointestinal Stromal Tumors Biopsy medicine.medical_treatment DNA Mutational Analysis Enucleation Case Report Physical examination PDGFRA Endosonography Predictive Value of Tests Biomarkers Tumor medicine Humans Thoracotomy Esophagus GiST medicine.diagnostic_test business.industry Gastroenterology General Medicine Esophageal Gastrointestinal Stromal Tumor Immunohistochemistry digestive system diseases Tumor Burden Surgery Esophagectomy Treatment Outcome medicine.anatomical_structure Mutation Neoplasm Grading Tomography X-Ray Computed business |
| Zdroj: | World Journal of Gastroenterology. 20:13632 |
| ISSN: | 1007-9327 |
| DOI: | 10.3748/wjg.v20.i37.13632 |
| Popis: | Gastrointestinal stromal tumors (GISTs) are rare mesenchymal neoplasms of the gastrointestinal tract. Less than 1% occurs in the esophagus. Surgery is the primary treatment for patients with GISTs. We report a 29-year-old male was admitted after the detection of a posterior mediastinal mass during work-up with routine examination. He did not have any disease-related symptoms. The physical examination was unremarkable. Chest computed tomographic scan, the barium esophagogram and endoscopic esophageal ultrasound showed benign neoplasm. The patient was performed an enucleation surgery through the right posterolateral thoracotomy. The pathology revealed a 13.0 cm × 12.0 cm × 5.0 cm mass. The tumor was CD117 (C-kit), PDGFRA and DOG1 positive. These findings were consistent with a GIST of the esophagus. So the diagnosis of GIST of esophagus was confirmed. The pathological diagnosis of low grade of GIST of esophagus was confirmed. The patient has no evidence of recurrence and is in good clinical conditions up-to date, five years after surgery. |
| Databáze: | OpenAIRE |
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