A model of actin-driven endocytosis explains differences of endocytic motility in budding and fission yeast

Autor:	Masoud Nickaeen, Thomas D. Pollard, Julien Berro, Boris M. Slepchenko
Rok vydání:	2022
Předmět:	Budding Chemistry Turgor pressure Endocytic cycle Cell Membrane Motility Saccharomyces cerevisiae Cell Biology Endocytosis Yeast Actins Cell biology Schizosaccharomyces Elongation Molecular Biology Actin
Zdroj:	Molecular Biology of the Cell. 33
ISSN:	1939-4586 1059-1524
DOI:	10.1091/mbc.e21-07-0362
Popis:	A comparative study (Sun et al., eLife, 2019) showed that the abundance of proteins at sites of endocytosis in fission and budding yeast is more similar in the two species than previously thought, yet membrane invaginations in fission yeast elongate two-fold faster and are nearly twice as long as in budding yeast. Here we use a three-dimensional model of a motile endocytic invagination (Nickaeen et al., MBoC, 2019) to investigate factors affecting elongation of the invaginations. We found that differences in turgor pressure in the two yeast species can largely explain the paradoxical differences observed experimentally in endocytic motility.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d55e686f5b52a5e34d2f695fae842a3 https://doi.org/10.1091/mbc.e21-07-0362 Zobrazit plný text záznamu