Evaluation of analgesic, sympathetic and motor effects of 1% and 2% lidocaine administered epidurally in dogs undergoing ovariohysterectomy
| Autor: | Manuel Martin-Flores, Verónica Gutierrez, Florencia Landivar, María Clausse, Paula Viviani, Verónica Cavilla, Pablo Nejamkin, Maria Jose del Sole, Matías Lorenzutti |
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| Rok vydání: | 2020 |
| Předmět: |
Anesthesia
Epidural Sympathetic Nervous System Lidocaine 040301 veterinary sciences Ovariectomy Analgesic Motor Activity Hysterectomy LIDOCAINE Fentanyl 0403 veterinary science ANALGESIA 03 medical and health sciences 0302 clinical medicine Dogs 030202 anesthesiology Heart rate DOG medicine Animals EPIDURAL Epidural administration Dexmedetomidine General Veterinary business.industry 04 agricultural and veterinary sciences Isoflurane Anesthesia Female OVARIOHYSTERECTOMY Tramadol purl.org/becyt/ford/4.3 [https] business purl.org/becyt/ford/4 [https] medicine.drug |
| Zdroj: | CONICET Digital (CONICET) Consejo Nacional de Investigaciones Científicas y Técnicas instacron:CONICET |
| ISSN: | 1467-2995 |
| Popis: | Objective: To compare, versus a control, the sensory, sympathetic and motor blockade of lidocaine 1% and 2% administered epidurally in bitches undergoing ovariohysterectomy. Study design: Randomized, blinded, controlled clinical trial. Animals: A total of 24 mixed-breed intact female dogs. Methods: All dogs were administered dexmedetomidine, tramadol and meloxicam prior to general anesthesia with midazolam–propofol and isoflurane. Animals were randomly assigned for an epidural injection of lidocaine 1% (0.4 mL kg−1; group L1), lidocaine 2% (0.4 mL kg−1; group L2) or no injection (group CONTROL). Heart rate (HR), respiratory rate (fR), end-tidal partial pressure of carbon dioxide (PE′CO2), and invasive systolic (SAP), mean (MAP) and diastolic (DAP) arterial pressures were recorded every 5 minutes. Increases in physiological variables were treated with fentanyl (3 μg kg−1) intravenously (IV). Phenylephrine (1 μg kg−1) was administered IV when MAP was |
| Databáze: | OpenAIRE |
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