Morphological and functional changes in skeletal muscle in type 2 diabetes mellitus: A systematic review and meta-analysis
| Autor: | Jardeson Rocha Filgueiras, Cleudiane Pereira Sales, Ivanilson Gomes da Silva, Cristiana Maria Dos Santos, Elias de Carvalho Magalhães Neto, Rebeca Barbosa da Rocha, Vinicius Saura Cardoso |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Physiotherapy Theory and Practice. :1-27 |
| ISSN: | 1532-5040 0959-3985 |
| DOI: | 10.1080/09593985.2022.2057375 |
| Popis: | Changes in the skeletal muscle are common in patients with type 2 diabetes mellitus (T2DM). These changes impair your motor skills.This systematic review aimed to investigate changes in skeletal muscle in patients with T2DM.The search was carried out in the PubMed, Scopus, and Web of Science databases until December 1, 2021. Observational studies that evaluated musculoskeletal changes in people with T2DM were included. The review was based on PRISMA recommendations. The primary parameters analyzed were muscle strength, muscle mass, muscle power, and muscle endurance.Forty-eight studies were included, with a total of 26,042 participants. The results revealed that T2DM is associated with a reduction in handgrip [-2.64 (CI 95% = -3.33 to -1.95, Z = -7.50,Individuals with T2DM present skeletal muscle impairments, mainly reduced muscle strength, mass, and endurance; increase in the thickness of the calcaneus tendon, and alteration in the proportion of type I and II fibers, even in the initial stage of the disease. |
| Databáze: | OpenAIRE |
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