Lower probability of FEV1 improvement in asthmatic children exposed to passive smoke

Autor: Velia Malizia, Salvatore Fasola, Roberta Antona, Laura Montalbano, Giovanna Cilluffo, Giuliana Ferrante, Stefania La Grutta
Přispěvatelé: Cilluffo, G, Fasola, S, Montalbano, L, Malizia, V, Ferrante, G, Antona, R, La Grutta, S
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Popis: Background: Guidelines advocate the use of spirometry to assess lung function in asthmatic. Inhaled corticosteroid(ICS) therapy is a mainstay of treatment for asthma, but the clinical response is variable. Aim: To assess the time variation of FEV1% in treated children with Persistent Asthma (PA). Methods: 110 children with PA, with two visits between September 2011 and December 2014 at the IBIM pediatric clinic were studied. Spirometry was performed using Pony FX, Cosmed, Italy; values were expressed as %pred using GLI-2012equation. The time trend of FEV1% for each subject was estimated through separate regressions. A linear regression model for the individual slopes (FEV1% average month variations) with respect to the intercepts (initial FEV1% values) was estimated. For the 71 children which had a FEV1%
Databáze: OpenAIRE