Lower probability of FEV1 improvement in asthmatic children exposed to passive smoke
Autor: | Velia Malizia, Salvatore Fasola, Roberta Antona, Laura Montalbano, Giovanna Cilluffo, Giuliana Ferrante, Stefania La Grutta |
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Přispěvatelé: | Cilluffo, G, Fasola, S, Montalbano, L, Malizia, V, Ferrante, G, Antona, R, La Grutta, S |
Jazyk: | angličtina |
Rok vydání: | 2015 |
Předmět: |
Spirometry
Pediatrics medicine.medical_specialty Lung passive smoke biology medicine.diagnostic_test business.industry Pony lung function respiratory system Passive smoke medicine.disease respiratory tract diseases Passive Smoke Exposure Asthmatic children medicine.anatomical_structure biology.animal Linear regression lung function asthmatic children passive smoke Medicine business Asthma asthmatic children |
Popis: | Background: Guidelines advocate the use of spirometry to assess lung function in asthmatic. Inhaled corticosteroid(ICS) therapy is a mainstay of treatment for asthma, but the clinical response is variable. Aim: To assess the time variation of FEV1% in treated children with Persistent Asthma (PA). Methods: 110 children with PA, with two visits between September 2011 and December 2014 at the IBIM pediatric clinic were studied. Spirometry was performed using Pony FX, Cosmed, Italy; values were expressed as %pred using GLI-2012equation. The time trend of FEV1% for each subject was estimated through separate regressions. A linear regression model for the individual slopes (FEV1% average month variations) with respect to the intercepts (initial FEV1% values) was estimated. For the 71 children which had a FEV1% |
Databáze: | OpenAIRE |
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