Contrast MRI Findings for Spinal Schwannoma as Predictors of Tumor Proliferation and Motor Status
| Autor: | Yoshimoto Ishikawa, Kenyu Ito, Naoki Ishiguro, Kei Ando, Shiro Imagama, Satoshi Tanaka, Kazuyoshi Kobayashi, Tetsuro Hida, Akiyuki Matsumoto, Masayoshi Morozumi, Mikito Tsushima |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty Pathology MIB-1 index Adolescent Urology Context (language use) Motor Activity Schwannoma 030218 nuclear medicine & medical imaging Lesion Young Adult 03 medical and health sciences 0302 clinical medicine Paralysis medicine Humans Potency Orthopedics and Sports Medicine Young adult Aged Cell Proliferation Retrospective Studies Motor status Aged 80 and over Spinal Neoplasms medicine.diagnostic_test Spinal schwannoma business.industry Heterogeneous intensity Magnetic resonance imaging Retrospective cohort study Middle Aged medicine.disease Magnetic Resonance Imaging Contrast MRI Female Neurology (clinical) medicine.symptom business Neurilemmoma 030217 neurology & neurosurgery |
| Zdroj: | SPINE. 42(3):E150-E155 |
| ISSN: | 0362-2436 |
| Popis: | STUDY DESIGN Retrospective analysis. OBJECTIVE The goal of this study was to examine the relationship of the proliferation potency based on the MIB-1 index and motor status with features of T2-weighted images (T2WI) and contrast T1-weighted images (T1WI) of spinal schwannoma. SUMMARY OF BACKGROUND DATA Spinal schwannomas account for 55% of spinal tumors, but the relationship of cellular proliferation with MRI findings for spinal schwannoma is unknown. METHODS The subjects were 48 patients (22 males and 26 females) with spinal schwannoma who were classified into three subgroups: iso/homo, high/rim, and hetero/hetero, based on T2WI/contrast T1WI. A retrospective analysis of tumor size and MIB-1 index was performed in the context of these MRI findings. Intraoperative findings and pre- and postoperative motor performance were also examined. RESULTS The average tumor size was 32.4 mm (range 10-130 mm) and the average MIB-1 index was 3.8% (range 1-12). In the three subgroups, there were no significant differences in sex, age, duration of disease, tumor lesion, and dumbbell type. In the hetero/hetero group, the tumor size was significantly greater and the MIB-1 index was significantly higher (both P |
| Databáze: | OpenAIRE |
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