Bioactivity of Phaeophytin a, α-Amyrin and lupeol from Brachystelma togoense Schltr
Autor: | Ibrahim Hamisu, Rachael Gbekele-Oluwa Ayo, James D. Habila, Abiche Ekalu |
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Jazyk: | angličtina |
Rok vydání: | 2019 |
Předmět: |
Brachystelma
Amyrin Traditional medicine biology Chemistry Multidisciplinary phaeophytin a General Chemistry Bioactivity Phaeophytin a α-amyrin and lupeol biology.organism_classification α-amyrin and lupeol lcsh:Chemistry chemistry.chemical_compound chemistry lcsh:QD1-999 bioactivity Kimya Ortak Disiplinler Lupeol |
Zdroj: | Journal of the Turkish Chemical Society, Section A: Chemistry, Vol 6, Iss 3, Pp 411-418 (2019) Volume: 6, Issue: 3 411-418 Journal of the Turkish Chemical Society Section A: Chemistry |
ISSN: | 2149-0120 |
Popis: | Phaeophytin a, α-amyrin and lupeol isolated from Brachystelma togoense were screened against S. aureus, E. coli, S. pneumonia, S. typhi, and C. albicans using Ciprofloxacin and Terbinafine as standards. The result showed that these phytochemicals displayed antimicrobial activity against the tested organisms with the zone of inhibition from 12 – 27 mm. The result of MIC showed that Phaeophytin a was most active against C. albicans (0.09 mg/ml). The MBC showed that phaeophytin a and lupeol were the most active against S. aureus, S. pneumonia and S. typhi (0.37 mg/ml). The result of MFC showed that phaeophytin a was most active against C. albicans (0.1875 mg/ml). The activity of these phytoconstituents in B. togoense justified ethnomedicinal uses of the plant. |
Databáze: | OpenAIRE |
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