Time trends in Swedish patch test data from 1992 to 2000. A multi-centre study based on age- and sex-adjusted results of the Swedish standard series
| Autor: | Magnus Lindberg, Torkel Fischer, Björn Edman, Berndt Stenberg |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Adult
Male Nickel allergy medicine.medical_specialty Allergy Population Dermatology Sex Factors Environmental health Epidemiology Prevalence medicine Humans Immunology and Allergy education Allergic contact dermatitis Sensitization Sweden education.field_of_study Chi-Square Distribution business.industry Age Factors Patch test Allergens Patch Tests medicine.disease Surgery medicine.anatomical_structure Dermatitis Allergic Contact Female business Contact dermatitis |
| Zdroj: | Contact Dermatitis. 56:205-210 |
| ISSN: | 1600-0536 0105-1873 |
| DOI: | 10.1111/j.1600-0536.2006.01063.x |
| Popis: | Allergic contact dermatitis is recognized as a public health problem and some major allergens have been subject to intervention aiming at lowering skin exposure. There is an obvious interest in evaluating the effect of such interventions. Population studies are difficult to perform and epidemiological studies based on clinical data from testing patients with contact dermatitis are common surrogates. Our objective was to gather Swedish clinical standard series test data on two occasions in order to monitor trends in sensitization rates. Consecutive patch test results from the Swedish standard series were collected from 9 centres from 1991 to 1993 and from 1999 to 2001. In total, 3680 and 3790 patients, respectively, were included. Crude, age-adjusted and age-stratified prevalence are given separately for women and men. Our top 10 allergens are much in line with newly published European test data. Significant changes among those allergens are increasing sensitization rates for Myroxylon pereirae and decreasing rates for colophony, 5-chloro-2-methyl-4-iso-thi-azo-lin-3-one, Amerchol L 101 and thiuram mix. Nickel allergy is decreasing among young women. Among less common allergens, a noteworthy increase of sensitization to 4-phenyl-en-diamine is found. In conclusion, significant trends in sensitization rates of important allergen, reflecting changes in exposure, have been found. |
| Databáze: | OpenAIRE |
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