Etiology, epidemiology, pathology, and advances in diagnosis, vaccine development, and treatment of Gallibacterium anatis infection in poultry: a review
| Autor: | Prakash Bhatt, Maddula Ramakoti Reddy, Asok Kumar Mariappan, Mohd Iqbal Yatoo, Kumaragurubaran Karthik, Dharanesha Narasinakuppe Krishnegowda, Ruchi Tiwari, Kuldeep Dhama, Palanivelu Munuswamy |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
040301 veterinary sciences
diagnosis Veterinary medicine virulence factors review Virulence Disease Microbiology 0403 veterinary science Antigenic Diversity Antibiotic resistance prevention SF600-1100 medicine Animals CRISPR Pathogen Poultry Diseases Anatis General Veterinary biology treatment poultry pathogenesis 0402 animal and dairy science Salpingitis 04 agricultural and veterinary sciences biology.organism_classification medicine.disease 040201 dairy & animal science Anti-Bacterial Agents Bacterial Vaccines epidemiology pathology Pasteurellaceae Pasteurellaceae Infections gallibacterium anatis control |
| Zdroj: | Veterinary Quarterly, Vol 40, Iss 1, Pp 16-34 (2020) The Veterinary Quarterly |
| ISSN: | 1875-5941 0165-2176 |
| Popis: | Gallibacterium anatis is a Gram-negative bacterium of the Pasteurellaceae family that resides normally in the respiratory and reproductive tracts in poultry. It is a major cause of oophoritis, salpingitis, and peritonitis, decreases egg production and mortality in hens thereby severely affecting animal welfare and overall productivity by poultry industries across Europe, Asia, America, and Africa. In addition, it has the ability to infect wider host range including domesticated and free-ranging avian hosts as well as mammalian hosts such as cattle, pigs and human. Evaluating the common virulence factors including outer membrane vesicles, fimbriae, capsule, metalloproteases, biofilm formation, hemagglutinin, and determining novel factors such as the RTX–like toxin GtxA, elongation factor-Tu, and clustered regularly interspaced short palindromic repeats (CRISPR) has pathobiological, diagnostic, prophylactic, and therapeutic significance. Treating this bacterial pathogen with traditional antimicrobial drugs is discouraged owing to the emergence of widespread multidrug resistance, whereas the efficacy of preventing this disease by classical vaccines is limited due to its antigenic diversity. It will be necessary to acquire in-depth knowledge on important virulence factors, pathogenesis and, concerns of rising antibiotic resistance, improvised treatment regimes, and novel vaccine candidates to effectively tackle this pathogen. This review substantially describes the etio-epidemiological aspects of G. anatis infection in poultry, and updates the recent development in understanding the pathogenesis, organism evolution and therapeutic and prophylactic approaches to counter G. anatis infection for safeguarding the welfare and health of poultry. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|