Effect of nonsurgical periodontal therapy on C-reactive protein and iron indices in hemodialysis patients
| Autor: | Indhuja Raveendran Saraswathi, Beena Unnikrishnan, Arun Sadasivan, Sheethel Menon Vrinda, Nikhil Das Chandradas, Elizabeth Koshi |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Bleeding on probing Gastroenterology renal insufficiency Scaling and root planing Internal medicine medicine periodontitis Dialysis Periodontitis treatment Transferrin saturation business.industry RK1-715 medicine.disease Chronic periodontitis inflammation Dentistry Periodontics Original Article Hemodialysis medicine.symptom business Kidney disease |
| Zdroj: | Journal of Indian Society of Periodontology Journal of Indian Society of Periodontology, Vol 25, Iss 6, Pp 485-490 (2021) |
| ISSN: | 0975-1580 0972-124X |
| Popis: | Background and Aim: The aim of the study was to evaluate the effect of nonsurgical periodontal therapy on clinical, renal, and hematological parameters at baseline and 3 months postoperatively on chronic kidney disease (CKD) patients undergoing hemodialysis. This comparative interventional study was conducted among CKD patients undergoing hemodialysis. Materials and Methods: This study included chronic periodontitis (CP) patients divided into three groups Group I: CKD patients undergoing hemodialysis for less than a year; Group II: CKD patients undergoing hemodialysis for more than a year; and Group III: systemically healthy CP patients. Clinical parameters (bleeding on probing [BOP], probing pocket depth (PPD), and clinical attachment level [CAL]) were recorded at baseline (T0), 1 month (T1), and 3 months after scaling and root planing (SRP) (T2). C-reactive protein (CRP) and transferrin saturation (TSAT) were observed at T0 and at T2. Paired t-test and Chi-square test were applied to find the statistical significance (P < 0.05 was considered statistically significant at 95% confidence interval) between the T0 and T2 time within the groups. Results: Clinical parameters such as PPD and CAL decreased with statistical significance in Group III alone, whereas BOP decreased with statistical significance in all the three groups. The study showed statistically significant reduction of CRP (in Group I and Group III) and TSAT increased with statistical significance in all the three groups after SRP. Conclusion: This suggests that SRP can bring an improvement in the systemic markers in CP patients under hemodialysis. However, we need a longitudinal study with a larger sample size to confirm the results. |
| Databáze: | OpenAIRE |
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