Myocardial work, an echocardiographic measure of post myocardial infarct scar on contrast-enhanced cardiac magnetic resonance
| Autor: | Victoria Delgado, Rachid Abou, Nina Ajmone Marsan, Mohammed El Mahdiui, Jeroen J. Bax, Rodolfo P. Lustosa, Rob J. van der Geest, Pieter van der Bijl |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Magnetic Resonance Imaging Cine Gadolinium contrast Work efficiency 030204 cardiovascular system & hematology 030218 nuclear medicine & medical imaging Cicatrix 03 medical and health sciences Percutaneous Coronary Intervention 0302 clinical medicine Internal medicine medicine Humans cardiovascular diseases Myocardial infarction Aged business.industry Myocardium Percutaneous coronary intervention Mean age Middle Aged medicine.disease Magnetic Resonance Imaging Blood pressure Echocardiography Conventional PCI Cardiology ST Elevation Myocardial Infarction Female Cardiology and Cardiovascular Medicine business Cardiac magnetic resonance |
| Zdroj: | American Journal of Cardiology, 151, 1-9. EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC |
| Popis: | This study investigates the relation of non-invasive myocardial work and myocardial viability following ST-segment elevation myocardial infarction (STEMI) assessed on late gadolinium contrast enhanced cardiac magnetic resonance (LGE CMR) and characterizes the remote zone using non-invasive myocardial work parameters. STEMI patients who underwent primary percutaneous coronary intervention (PCI) were included. Several non-invasive myocardial work parameters were derived from speckle tracking strain echocardiography and sphygmomanometric blood pressure, e.g.: myocardial work index (MWI), constructive work (CW), wasted work (WW) and myocardial work efficiency (MWE). LGE was quantified to determine infarct transmurality and scar burden. The core zone was defined as the segment with the largest extent of transmural LGE and the remote zone as the diametrically opposed segment without LGE. A total of 53 patients (89% male, mean age 58 +/- 9 years) and 689 segments were analyzed. The mean scar burden was 14 +/- 7% of the total LV mass, and 76 segments (11%) demonstrated transmural hyperenhancement, 280 (41%) non-transmural hyperenhancement and 333 (48%) no LGE. An inverse relation was observed between segmental MWI, CW and MWE and infarct transmurality (p < 0.05). MWI, CW and MWE were significantly lower in the core zone compared to the remote zone (p |
| Databáze: | OpenAIRE |
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