Low-dose weekly supplementation of iron and/or zinc does not affect growth among Bangladeshi infants
| Autor: | Robert E. Black, Abdullah H Baqui, Laura E. Caulfield, C. L. Fischer Walker, Salahuddin Ahmed, Nazma Begum, S El Arifeen, M. Yunus, K. Zaman |
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| Rok vydání: | 2007 |
| Předmět: |
Rural Population
Iron Riboflavin Medicine (miscellaneous) Physiology chemistry.chemical_element Growth Zinc Affect (psychology) law.invention Pharmacotherapy Randomized controlled trial law Humans Medicine Bangladesh Nutrition and Dietetics business.industry Body Weight Low dose Infant social sciences bacterial infections and mycoses medicine.disease Body Height humanities Malnutrition Biochemistry chemistry Dietary Supplements Arm population characteristics Drug Therapy Combination medicine.symptom business Weight gain geographic locations |
| Zdroj: | European Journal of Clinical Nutrition. 63:87-92 |
| ISSN: | 1476-5640 0954-3007 |
| Popis: | To determine the effect of low-dose weekly supplementation with iron, zinc or both on growth of infants from 6 to 12 months of age.A total of 645 breastfed infants age 6 months who were not severely anemic (Hbor = 90 g l(-1)) or severely malnourished (weight-for-ageor = 60% median) were randomized to receive 20 mg iron and 1 mg riboflavin; 20 mg zinc and 1 mg riboflavin; 20 mg iron, 20 mg zinc and 1 mg riboflavin; or riboflavin alone (control) weekly for 6 months.Baseline characteristics were similar among the four supplementation groups. Weight, length and mid-upper arm circumference were assessed at baseline, 8, 10 and 12 months of age. There was no interaction of iron and zinc when given in a combined supplement on either weight or length (P0.05). There were no effects of either iron or zinc on the rate of length or weight gain for all infants or when stratified by baseline Hb concentration.Weekly supplementation of 20 mg Fe, 20 mg Zn, or both does not benefit growth among infants 6-12 months of age in rural Bangladesh, a region with high rates of anemia and zinc deficiency. |
| Databáze: | OpenAIRE |
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