Decrease in cerebellar blood flow in patients with Friedreich’s ataxia: A TC-HMPAO SPECT study of three cases
| Autor: | J.L. Pelletier, N. Dueret, R. Dumas, L. Septien, M. Giroud |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Adult
Male Ataxia Central nervous system Computed tomography Technetium Tc 99m Exametazime Atrophy Cerebellum Oximes medicine Humans In patient Tomography Emission-Computed Single-Photon medicine.diagnostic_test business.industry Magnetic resonance imaging Organotechnetium Compounds General Medicine Blood flow medicine.disease Hmpao spect medicine.anatomical_structure Neurology Friedreich Ataxia Regional Blood Flow Female Neurology (clinical) medicine.symptom Nuclear medicine business |
| Zdroj: | Neurological Research. 16:342-344 |
| ISSN: | 1743-1328 0161-6412 |
| DOI: | 10.1080/01616412.1994.11740251 |
| Popis: | Three cases of Friedreich’s ataxia were submitted to diverse neuroradiological procedures in order to determine the extent of atrophic processes in the central nervous system. All patients underwent computerized-tomography scan, Magnetic Resonance Imaging, and HMPA-single Photon emission computerized tomography studies, focusing in cerebellar lobes. A slight atrophy was observed in the vermis and the cerebellar lobes with CT scan and MRI. In contrast a significant decrease in cerebellar blood flow was shown by TC-HMPAE SPECT study. The significance of these findings in understanding physiopathological mechanisms in Friedreich’s ataxia is discussed. [Neurol Res 1994; 16: 342-344] |
| Databáze: | OpenAIRE |
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