Residual mother-to-child transmission of HIV in Burkina Faso
| Autor: | A. Y. Ky, Arouna Ouedraogo, C Ki Toe, Ismael Diallo, P. T. Sanou, Lassana Sangaré, R Ouedraogo Traore, Mahamoudou Sanou, A Ky Ba, J. Catraye, L Toguyeni Tamini, Idrissa Sanou |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Pediatrics
medicine.medical_specialty Mother to child transmission Nevirapine business.industry Transmission (medicine) Burkina Faso HIV/AIDS mother-to-child transmission antiretroviral drugs pregnant women General Chemical Engineering Human immunodeficiency virus (HIV) Psychological intervention virus diseases Disease medicine.disease_cause medicine.disease Acquired immunodeficiency syndrome (AIDS) medicine Prospective cohort study business medicine.drug |
| Zdroj: | African Journal of Clinical and Experimental Microbiology; Vol 18, No 2 (2017); 102-109 |
| ISSN: | 1595-689X |
| Popis: | Background: Burkina Faso is one of the countries in West Africa most affected by the HIV/AIDS pandemic, despite the implementation of a mother-to-child HIV transmission prevention program as a strategy to reduce the risk of vertical transmission of the disease. Objective: To assess the current risk of mother-to-child transmission of HIV in Burkina Faso. Materials and methods: A prospective study was conducted between December 2014 and July 2016, in the 13 health regions of Burkina Faso. Women who were screened HIV-positive during a prenatal consultation were followed until delivery. Their babies received dry blood spot (DBS) at birth, at week 6 and at 1year, to screen for HIV. Results: Overall, 186 pregnant women were included in the study, with a mean age of 29.17±6.13 years. Of their children, 430 DBS actually received a PCR test, giving a 91.1% PCR implementation rate. After analyses, 6 (1.3%) babies were identified as carriers of HIV1. The newborn’s serological status was associated with delivery pattern (p=0.000), the administration of antiretroviral drugs to the mother after delivery (p=0.0064), the administration of Nevirapine to the newborn at birth (p=0.022), the use of contraceptive methods after delivery (p=0.028) and the presence of breast affections/infections since delivery (p=0.013). Conclusion: The results of our study are encouraging and demonstrate the effectiveness of interventions in the mother-tochild prevention program (PMTCT) for HIV-positive pregnant women can be improved through early initiation of triple therapy in early pregnancy and improved adherence to antiretroviral (ARV) therapy. Keywords: Burkina Faso, HIV/AIDS, mother-to-child transmission, antiretroviral drugs, pregnant women |
| Databáze: | OpenAIRE |
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