| Autor: |
Le Tuan Anh, Hoang, Le Ba, Vinh, Thao, Thi, Phan, Van Kiem, Thi, Hai Yen Pham, Bach, Long Giang, Tran, Manh Hung, Thi, Phuong Anh Tran, Kim, Young Ho |
| Rok vydání: |
2022 |
| DOI: |
10.6084/m9.figshare.13065992 |
| Popis: |
A new compound, physalucoside A (1), together with seven withanolides (2–8) and three flavonoids (9–11), were isolated from Physalis angulata L. (Solanaceae), a medicinal plant native to Vietnam. The chemical structures of these compounds were elucidated by one- and two-dimensional NMR spectra, high-resolution electrospray ionization mass spectrometry analyses, and chemical reactivity. The anti-inflammatory and cytotoxic activities of isolated compounds were also evaluated. These data suggest that the anti-inflammatory activity of P. angulata is due primarily to its withanolide content. This study demonstrates the potential of withanolides as promising candidates for the development of new anti-inflammatory drugs. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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