| Autor: |
Giorgio Caturegli, Shrey Kapoor, Vladimir Ponomarev, Bo Soo Kim, Glenn J.R. Whitman, Wendy Ziai, Sung-Min Cho, Lucy Q. Zhang, Yunis Mayasi, Aaron Gusdon, Bahattin Ergin, Steven Keller, Matthew Acton, Hannah Rando, Diane Alejo, Kate Calligy, Scott Anderson, Benjamin Shou, Pedro A. Mendez-Tellez, Henry Chang, Marc Sussman, Christopher Wilcox, Patricia Brown, Anna Peeler |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
JTCVS Techniques. 15:111-122 |
| ISSN: |
2666-2507 |
| DOI: |
10.1016/j.xjtc.2022.07.026 |
| Popis: |
Extracorporeal membrane oxygenation (ECMO) carries a high morbidity of acute brain injury (ABI) with resultant mortality increase. Transcranial Doppler (TCD) allows real-time characterization of regional cerebral hemodynamics, but limited data exist on the interpretation of microembolic signals (MES) in ECMO.This prospective cohort study was conducted at a single tertiary care center, November 2017 through February 2022, and included all adult patients receiving venoarterial (VA) and venovenous (VV) ECMO undergoing TCD examinations, which all included MES monitoring.Of 145 patients on ECMO who underwent at least 1 TCD examination, 100 (68.9%) patients on VA-ECMO received 187 examinations whereas 45 (31.1%) patients on VV-ECMO received 65 examinations (TCD analysis in a large cohort of patients on ECMO demonstrates a significant number of MES, especially in patients on VA-ECMO with intra-aortic balloon pump, and/or left ventricular assist device. However, clinical associations and significance of TCD MES remain unresolved and warrant further correlation with systematic imaging and long-term neurologic follow-up. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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