Solid Pseudopapillary Neoplasms of the Pancreas: a Single-Center Experience and Review of the Literature
Autor: | Moustafa Allam, Jennifer Watkins, Nikolaos Machairas, Camila Hidalgo Salinas, Ioannis D. Kostakis, Giuseppe Fusai |
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Rok vydání: | 2021 |
Předmět: |
Adult
Male medicine.medical_specialty Adolescent medicine.medical_treatment Splenectomy Single Center Young Adult 03 medical and health sciences Pancreatectomy 0302 clinical medicine medicine Humans Pancreas Pathological Aged Retrospective Studies business.industry Gold standard Gastroenterology Perioperative Middle Aged Surgery Pancreatic Neoplasms Radiation therapy medicine.anatomical_structure Oncology 030220 oncology & carcinogenesis Female 030211 gastroenterology & hepatology Neoplasm Recurrence Local business |
Zdroj: | Journal of Gastrointestinal Cancer. 53:460-465 |
ISSN: | 1941-6636 1941-6628 |
DOI: | 10.1007/s12029-021-00638-6 |
Popis: | Pancreatic solid pseudopapillary neoplasms (SPNs) are rare borderline tumours mainly affecting young female patients. The number of patients diagnosed with SPNs has increased significantly in the last decades owing to the increased use of cross-sectional imaging investigating different abdominal symptoms, whilst a significant proportion are incidentally discovered during the process of evaluating other pathologies. We herein present our institutional experience of patients with SPN who underwent curative resection focusing on clinical, pathological features, and the long-term outcomes. All patients undergoing pancreatectomy in our institution for SPN from January 2010 until December 2018 were included. Clinical, perioperative, histological, and long-term outcomes were collected and analysed. During the inclusion period, a total of 19 patients had a pathological diagnosis of SPNs after surgical resection. Sixteen of them were female (84%), while the median patient age was 30 (range 16–66) years. Nine patients (47%) underwent distal pancreatectomy and splenectomy, 2 (11%) underwent spleen preserving distal pancreatectomy, 6 (32%) underwent pancreatoduodenectomy, one (5%) underwent total pancreatectomy, and one (5%) central pancreatectomy. Seventeen patients underwent R0 resection. During a median follow-up of 23 months, no tumour recurrence or death was recorded. In our experience, SPNs are rare tumours with low malignant potentials. Surgical resection remains the gold standard treatment and is associated with good prognosis. |
Databáze: | OpenAIRE |
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