Effectiveness of Education and an Antibiotic-Control Program in a Tertiary Care Hospital in Thailand

Autor: Boonyasit Warachan, Thana Khawcharoenporn, Victoria J. Fraser, Anucha Apisarnthanarak, Somwang Danchaivijitr, Thomas C. Bailey, Julajak Limsrivilai
Rok vydání: 2006
Předmět:
Zdroj: Clinical Infectious Diseases. 42:768-775
ISSN: 1537-6591
1058-4838
DOI: 10.1086/500325
Popis: Background. We conducted a study to evaluate the impact of education and an antibiotic-control program on antibiotic-prescribing practices antibiotic consumption antimicrobial resistance and cost of antibiotics in a tertiary care hospital in Thailand. Methods. A study of the year before and the year after the intervention was performed. Inpatient antibiotic prescriptions were prospectively observed. Demographic characteristics hospital unit indication for antibiotic prescription appropriateness of antibiotic use reasons for inappropriate antibiotic use antibiotic consumption (i.e. the rate of antibiotic use) bacterial resistance and antibiotic cost data were collected. Interventions included education introduction of an antibiogram use of antibiotic prescription forms and prescribing controls. Results. After the intervention there was a 24% reduction in the rate of antibiotic prescription (640 vs. 400 prescriptions/1000 admissions; P < .001). The incidence of inappropriate antibiotic use was significantly reduced (42% vs. 20%; P < .001). A sustained reduction in antibiotic use was observed (R(2) = 0.692; P
Databáze: OpenAIRE