Functionally Assessing the Age-Related Decline in the Detection Rate of Photons by Cone Photoreceptors
| Autor: | Asma Braham chaouche, Maryam Rezaei, Daphné Silvestre, Angelo Arleo, Rémy Allard |
|---|---|
| Přispěvatelé: | Université de Montréal (UdeM), McGill University = Université McGill [Montréal, Canada], Institut de la Vision, Centre National de la Recherche Scientifique (CNRS)-Sorbonne Université (SU)-Institut National de la Santé et de la Recherche Médicale (INSERM), HAL-SU, Gestionnaire, Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS) |
| Rok vydání: | 2021 |
| Předmět: |
0303 health sciences
Aging contrast sensitivity noise genetic structures Cognitive Neuroscience Mini Review photon noise equivalent input noise Aging Neuroscience Neurosciences. Biological psychiatry. Neuropsychiatry photoreceptors detection of photons eye diseases 03 medical and health sciences 0302 clinical medicine cones motion [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC] [SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC] sense organs 030217 neurology & neurosurgery 030304 developmental biology RC321-571 |
| Zdroj: | Frontiers in Aging Neuroscience Frontiers in Aging Neuroscience, Vol 13 (2021) Frontiers in Aging Neuroscience, Frontiers, 2021, 13, ⟨10.3389/fnagi.2021.744444⟩ Frontiers in Aging Neuroscience, 2021, 13, ⟨10.3389/fnagi.2021.744444⟩ |
| ISSN: | 1663-4365 |
| DOI: | 10.3389/fnagi.2021.744444⟩ |
| Popis: | International audience; Age-related decline in visual perception is usually attributed to optical factors of the eye and neural factors. However, the detection of light by cones converting light into neural signals is a crucial intermediate processing step of vision. Interestingly, a novel functional approach can evaluate many aspects of the visual system including the detection of photons by cones. This approach was used to investigate the underlying cause of age-related visual decline and found that the detection rate of cones was considerably affected with healthy aging. This functional test enabling to evaluate the detection of photons by cones could be particularly useful to screen for retinal pathologies affecting cones such as age-related macular degeneration. However, the paradigm used to functionally measure the detection of photons was complex as it was evaluating many other properties of the visual system. The aim of the current mini review is to clarify the underlying rationale of functionally evaluating the detection of photons by cones, describe a simpler approach to evaluate it, and review the impact of aging on the detection rate of cones. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|