Pattern of the ventilatory response to transient hypoxia in man: differences from transient hypercapnic test
| Autor: | Ch. Grimaud, M. Fornaris, Yves Jammes, C. Guillot |
|---|---|
| Rok vydání: | 1979 |
| Předmět: |
Adult
Male Progressive change Physiology Nitrogen Biochemistry Hypercapnia medicine Humans Child Hypoxia Tidal volume Inhalation business.industry Transient hypoxia Respiration Hypoxia (medical) Carbon Dioxide Middle Aged Anesthesia Normal children Significant positive correlation Female medicine.symptom business |
| Zdroj: | Archives internationales de physiologie et de biochimie. 87(2) |
| ISSN: | 0003-9799 |
| Popis: | The pattern of change in ventilatory variables after inhalation of pure N2 for two breaths was studied in normal children and adults. In six subjects the trends of change were compared to the ventilatory response to transient hypercapnia. We observed differences in the patterns of increasing ventilation with an initial abrupt increase of tidal volume for transient hypoxia and a progressive change for hypercapnia. In both cases respiratory frequency was progressively but unsystematically enhanced. A highly significant positive correlation was demonstrated between individual sensitivities to CO2 and O2, with a greater response to hypercapnia (5.6 time) than to hypoxia. Finally, a very short-latency decrease in expiratory duration occurred in the first breath after inhalation of hypercapnic mixture, supporting the recent data of Cunningham et al. (1977). |
| Databáze: | OpenAIRE |
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