Intraocular Melanoma Linked to Occupations and Chemical Exposures
| Autor: | David K. Ahn, Aston Da, E. A. Holly, Allan H. Smith |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Male
Uveal Neoplasms medicine.medical_specialty Northwestern United States Chemical compound Ultraviolet Rays Epidemiology medicine.disease_cause Asbestos Occupational medicine Random Allocation chemistry.chemical_compound Bias Recall bias Internal medicine Confidence Intervals Odds Ratio Southwestern United States medicine Ultraviolet light Humans Occupations Melanoma business.industry Environmental Exposure Odds ratio Confidence interval Surgery Occupational Diseases chemistry Case-Control Studies Chemical Industry Mental Recall business |
| Zdroj: | Epidemiology. 7:55-61 |
| ISSN: | 1044-3983 |
| DOI: | 10.1097/00001648-199601000-00010 |
| Popis: | We conducted a case-control study in the western United States to determine the relation between occupations or chemical exposures and increased risk of uveal melanoma. Among men (221 patients, 447 controls), we found increased risks for occupational groups who had intense exposure to ultraviolet light [odds ratio (OR) = 3.0; 95% confidence interval (CI) = 1.2-7.8], welding exposure (OR = 2.2; 95% CI = 1.3-3.5), and asbestos exposure (OR = 2.4; 95% CI = 1.5-3.9 for most likely exposed). The highest odds ratio was for the small number of men (nine cases, three controls) who were chemists, chemical engineers, and chemical technicians (OR = 5.9; 95% CI = 1.6-22.7). Odds ratios also were elevated for exposures to antifreeze, formaldehyde, pesticides, and carbon tetrachloride, but these findings, based on recall of specific chemical exposures, are more subject to recall bias than the findings based on occupational groups. |
| Databáze: | OpenAIRE |
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