Monoterpene indole alkaloids from Melodinus cochinchinensis (Lour.) Merr

Autor:	Xiao-Feng Wang, Ren-Jie Wei, Qiang-Qiang Fang, Wan-Ying He, Kun Jiang, Shi-Jin Qu, Jun-Jie Tan, Chang-Heng Tan
Rok vydání:	2021
Předmět:	Pharmacology Apocynaceae China Magnetic Resonance Spectroscopy Optical Rotation Plant Stems Spectrophotometry Infrared Plant Extracts Drug Discovery General Medicine Secologanin Tryptamine Alkaloids Chromatography High Pressure Liquid
Zdroj:	Fitoterapia. 157
ISSN:	1873-6971
Popis:	Melodicochinines A - D (1-4), four new monoterpene indole alkaloids (MIAs), along with 21 known ones, were isolated from the stems and twigs of Melodinus cochinchinensis. Their structures were elucidated on the basis of extensive spectroscopic analysis. A ubiquitin-rhodamine 110 assay showed that 11-methyloxytabersonine had potential inhibitory effect against ubiquitin-specific protease 7 (USP7).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6858cd6e6e8f9fd4d53ad7433245a9ec https://pubmed.ncbi.nlm.nih.gov/34974140 Zobrazit plný text záznamu Full Text from ScienceDirect