Effects of Nigeria Ekete light crude oil on plasma electrolytes, packed cell volume (PCV) and lipids profile in wistar (Rattus norvegicus) rats
| Autor: | Alaba Olumide Ojo, Femmymale Taiye F, Bamidele Olubayode, Babatunde Lawrence D, S I Jaja |
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| Rok vydání: | 2015 |
| Předmět: |
chemistry.chemical_classification
Light crude oil Chromatography Dose Chemistry Electrolytes crude oil plasma lipids profile packed cell volume Crude oil Applied Microbiology and Biotechnology Plasma electrolytes Animal science Hydrocarbon Oral administration Genetics Ingestion Packed cell volume - PCV Agronomy and Crop Science Molecular Biology Biotechnology |
| Zdroj: | African Journal of Biotechnology; Vol 14, No 24 (2015); 2047-2051 |
| ISSN: | 1684-5315 |
| DOI: | 10.5897/ajb2014.13972 |
| Popis: | Hydrocarbon is known to alter blood parameters; some of these blood parameters may affect the activities of certain systems like cardiovascular system. Hydrocarbon gets into man and animal either through ingestion of contaminated food and water, bio-concentration through food chain, occupational exposure or by using hydrocarbon products. Effects of crude oil on plasma electrolytes, packed cell volume (PCV) and plasma lipid profile were examined in male Rattus norvegicus in this study. Crude oil was administered orally at dosages of 5 ml/kg (group I), 10 ml/kg (group II) and 20 ml/kg (group III) for two weeks while the control group received drinking water only. The result shows a reduction in packed cell volume in all treated groups compared to control (37.14±0.85, P < 0.05) and a significant (P < 0.05) increase in plasma sodium level in treated groups compared to control (22.486±2.983 mg/L) while there was no significant alteration in plasma lipids profile of the treated groups relative to the control. Oral administration of crude oil significantly altered the plasma levels of electrolytes and PCV. Key words: Electrolytes, crude oil, plasma lipids profile, packed cell volume. |
| Databáze: | OpenAIRE |
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