| Autor: |
Hui Zhuan Tan, Benson Siow, Jason Chon Jun Choo, Alwin Hwai Liang Loh, Fiona Hui Ing Yeo, Irene Mok, Puay Hoon Tan, Choong Meng Chan, Chieh Suai Tan, Keng Thye Woo, Cynthia Ciwei Lim |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
International Urology and Nephrology. 54:2365-2373 |
| ISSN: |
1573-2584 |
| Popis: |
Patients undergoing kidney biopsy are increasingly older. We aimed to evaluate the clinical utility of kidney biopsy, long-term clinical outcomes, and safety of high-risk biopsies in older adults undergoing kidney biopsy in a multi-ethnic Southeast Asian cohort.We performed a single-center retrospective study of older patients (age ≥ 60 years) who underwent native kidney biopsies between June 2011 and March 2015. The primary long-term outcome of interest was a composite of ESKD or death. The safety outcome of interest was post-biopsy bleeding in the high-risk subgroup, defined by serum creatinine 150 µmol/l.Older adults accounted for 153 of 545 (28.1%) native renal biopsies performed. The median age of these older adults was 66.6 (IQR 63.0, 70.6) years. Kidney dysfunction was frequent and severe in this cohort, with 41.2% having eGFR 30 ml/min/mOur study confirmed the utility of kidney biopsy in older adult patients for diagnosis and management, although risk counselling and close monitoring for bleeding complications is necessary. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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