Evaluation of optimized b-value sampling schemas for diffusion kurtosis imaging with an application to stroke patient data
| Autor: | Guang Yang, Mingxia Fan, Yong-Di Zhou, Lingfang Ying, Dongrong Xu, Dazhi Yin, Fan Song, Min-Xiong Zhou, Xu Yan |
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| Rok vydání: | 2013 |
| Předmět: |
Male
Stroke patient Computer science Health Informatics Visual Basic for Applications computer.software_genre Sensitivity and Specificity Article Data acquisition Voxel Schema (psychology) Image Interpretation Computer-Assisted Humans Radiology Nuclear Medicine and imaging Diffusion Kurtosis Imaging Aged Radiological and Ultrasound Technology Estimation theory Brain Reproducibility of Results Signal Processing Computer-Assisted Middle Aged Image Enhancement Computer Graphics and Computer-Aided Design Stroke Diffusion Tensor Imaging Data Interpretation Statistical Sample Size Female Computer Vision and Pattern Recognition Data mining computer Algorithms Diffusion MRI |
| Zdroj: | Computerized Medical Imaging and Graphics. 37:272-280 |
| ISSN: | 0895-6111 |
| Popis: | Diffusion kurtosis imaging (DKI) is a new method of magnetic resonance imaging (MRI) that provides non-Gaussian information that is not available in conventional diffusion tensor imaging (DTI). DKI requires data acquisition at multiple b-values for parameter estimation; this process is usually time-consuming. Therefore, fewer b-values are preferable to expedite acquisition. In this study, we carefully evaluated various acquisition schemas using different numbers and combinations of b-values. Acquisition schemas that sampled b-values that were distributed to two ends were optimized. Compared to conventional schemas using equally spaced b-values (ESB), optimized schemas require fewer b-values to minimize fitting errors in parameter estimation and may thus significantly reduce scanning time. Following a ranked list of optimized schemas resulted from the evaluation, we recommend the 3b schema based on its estimation accuracy and time efficiency, which needs data from only 3 b-values at 0, around 800 and around 2600 s/mm2, respectively. Analyses using voxel-based analysis (VBA) and region-of-interest (ROI) analysis with human DKI datasets support the use of the optimized 3b (0, 1000, 2500 s/mm2) DKI schema in practical clinical applications. |
| Databáze: | OpenAIRE |
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