Personalized multitarget biologic injection in the spine: prospective case series of multitarget platelet-rich plasma for low back pain

Autor:	Edilson S Machado, Mary A Ambach, José MP Caldas, Jason J Wei, Markus Bredemeier
Rok vydání:	2022
Předmět:	Biological Products Embryology Platelet-Rich Plasma Biomedical Engineering Humans Intervertebral Disc Low Back Pain Pain Measurement nervous system diseases
Zdroj:	Regenerative Medicine. 17:11-22
ISSN:	1746-076X 1746-0751
DOI:	10.2217/rme-2021-0019
Popis:	Aim: To evaluate the use of a multitarget platelet-rich plasma (PRP) injection approach for the treatment of chronic low back pain (LBP). Materials & Methods: Forty-six patients with more than 12 weeks of LBP who failed conservative treatments were injected with PRP into the facet joints, intervertebral discs, epidural space and/or paravertebral muscles. Visual analog pain scale and Roland-Morris Disability Questionnaire scores were measured at baseline and predefined intervals. Results: Mean visual analog pain scale was reduced from 8.48 to 5.17 and mean Roland-Morris Disability Questionnaire from 18.0 to 10.98 at 12 weeks (p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67f2bc819b2f2690413dc6e445bcd3cc https://doi.org/10.2217/rme-2021-0019 Zobrazit plný text záznamu