Routine Coronary Angiography is Still the Key Test for Patients Eligible for Lung Transplantation Also for Those With No Symptoms and With High Risk of Coronary Artery Disease

Autor: Wojtek Karolak, Krystyna Pastwa, Salma Ali Addo, Salin Khan, Reema Shinde, Ikram Mukhtar Nuur, Adith Kumaravel, Feven Kifle Reta, Jacek Wojarski, Marcin Maruszewski, Elżbieta Woźniak-Grygiel, Michał Chmielecki, Anna Frankiewicz, Adam Nagajewski, Mary Ene Abba, Monika Łącka, Sławomir Żeglen
Rok vydání: 2022
Předmět:
Zdroj: Transplantation proceedings. 54(4)
ISSN: 1873-2623
Popis: Background. Coronary artery disease (CAD) has a considerable morbidity and mortality effect on the outcomes of a lung transplant. Currently, coronary angiography is performed as part of the pretransplant evaluation process. Unfortunately, there are no clear guidelines about performing cardiac angiography in lung transplant candidates. Background. The aim of our work is to find a correlation between cardiovascular risk and coronary arterial status to optimize the selection of patients for coronary angiography prior transplantation. Methods. We retrospectively analyzed 48 patients in whom coronary angiography and cardiac catheterization was performed during assessment for bilateral lung transplantation at the Medical University of Gdansk from 2018 to 2021. The coronary artery disease status was classified into 2 categories: without any stenosis and with stenosis. For each patient, the 10-year cardiovascular risk was estimated by using a Systematic COronary Risk Evaluation calculator modified for the Polish population. Results. Coronary stenosis was detected in 15 patients during angiography (31%). The group with coronary stenosis had a median SCORE risk of 8%, which is considered as high risk, and in patients without stenosis it was 5%, which is also considered a high risk. Median mean pulmonary artery pressure in patients with stenosis was the same as that in patients without stenosis (23 mm Hg). Conclusions. CAD among lung transplant candidates cannot be predicted by risk factors, so coronary angiography is very important as a part of the evaluation process. Because pulmonary hypertension has a big impact on surveillance after transplantation, performing heart catheterization during the qualification process is crucial.
Databáze: OpenAIRE
Externí odkaz: