Ano-genital distance in healthy Nigerian full-term newborn infants
| Autor: | J. B. E. Elusiyan, Alphonsus N. Onyiriuka |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Fetus
medicine.medical_specialty Obstetrics business.industry medicine.drug_class Birth weight Anogenital distance ano-genital distance newborn nigerian 030209 endocrinology & metabolism Anthropometry RC648-665 Androgen Diseases of the endocrine glands. Clinical endocrinology 03 medical and health sciences 0302 clinical medicine 030225 pediatrics medicine Gestation Sex organ business Full Term |
| Zdroj: | Sri Lanka Journal of Diabetes Endocrinology and Metabolism, Vol 6, Iss 2, Pp 35-39 (2016) |
| ISSN: | 2012-998X |
| Popis: | Background/Aim: In humans, anogenital distance (AGD) appears to provide a reliable guide to androgen exposure during fetal life. The aim of the present study is to determine the normal values for AGD in Nigerian newborns of both genders and to determine its association with birth weight and length. Methods: For this descriptive cross-sectional study, 895 (448 males and 447 females) healthy full-term (37 to 42 weeks’ gestation) infants between the age of 6 to 72 hours delivered in two Nigerian hospitals were recruited for this evaluation. A standardized anthropometric protocol was used to measure AGD, ano-scrotal distance (ASD) and ano-fourchette distance (AFD). The birth weight and the length of all the subjects were also measured and recorded. Results: There was a total of 895 (448 males and 447 females) subjects for the study. The mean birth weights were 3288±472g (95% CI = 3244 - 3332) and 3125±552g (95% CI= 3074 - 3176) for male and female infants, respectively; p < 0.01. The mean AGDs (±SD) at birth were 28.3±3.9 mm (95% CI = 27.9 - 28.7) in males and 15.2±2.4 mm (95% CI= 15.0 - 15.4) in females; p < 0.001. The ratio of the male-to-female ano-genital distance (ASD/AFD) was 1.7. The adjusted AGD [AGDASD / birth weight (mm/kg)] and [AGDAFD / birth weight (mm/kg)] was 8.7 and 4.9 for male and female newborn infants, respectively. Conclusion: The results of this study provide reliable normative values that can be used as a standard with regard to AGD in Nigerian male and female newborns at birth. |
| Databáze: | OpenAIRE |
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