Synaptic interaction between catecholaminergic neurons and substance P-immunoreactive axons in the caudal part of the nucleus of the solitary tract of the rat: demonstration by the electron microscopic mirror technique
| Autor: | Hiroshi Takagi, Yoshiyuki Kubota, John Powell, Yumiko Morishima, A. D. Smith |
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| Předmět: |
Male
Tyrosine 3-Monooxygenase Immunoelectron microscopy Substance P Immunoenzyme Techniques chemistry.chemical_compound medicine Animals Axon Molecular Biology Medulla Oblongata Tyrosine hydroxylase Synaptic interaction General Neuroscience Solitary tract Rats Microscopy Electron medicine.anatomical_structure nervous system chemistry Synapses Catecholaminergic cell groups Neurology (clinical) Neuroscience Nucleus Developmental Biology |
| Zdroj: | Scopus-Elsevier |
| Popis: | The 'mirror technique' was applied in immunoelectron microscopy to demonstrate the synaptic relationship between neuronal structures containing catecholamines and substance P in the caudal part of nucleus of the solitary tract in the rat, using antisera against tyrosine hydroxylase and substance P. Substance P-immunoreactive axon terminals were shown to make two types of synaptic contacts (asymmetrical and symmetrical) with catecholaminergic neurons. It is concluded that substance P afferents can directly affect catecholaminergic neurons in this nucleus via synapses. |
| Databáze: | OpenAIRE |
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