Laparotomy for the staging of Hodgkin's disease in children
| Autor: | Robert E. Hittle, Hart Isaacs, Myron Karon, Daniel M. Hays |
|---|---|
| Rok vydání: | 1972 |
| Předmět: |
Male
medicine.medical_specialty Adolescent medicine.medical_treatment Biopsy Splenectomy Disease Bone Marrow Laparotomy medicine Methods Humans Stage (cooking) Child Chemotherapy medicine.diagnostic_test business.industry Infant General Medicine Hodgkin Disease Surgery Radiation therapy Prior Therapy Diagnostic Techniques Surgical Liver Child Preschool Pediatrics Perinatology and Child Health Female Lymph Nodes business |
| Zdroj: | Journal of pediatric surgery. 7(5) |
| ISSN: | 0022-3468 |
| Popis: | A review of the technique and early results of laparotomy for staging in 20 children with Hodgkin's disease, including 18 without prior therapy, is presented. Laparotomy altered the clinical stage, either “upward” or “down-ward”, in one-half of the patients. This stage change resulted in major modifications in therapy. No patients have developed abdominal Hodgkin's disease subsequent to a negative (complete) staging laparotomy. The presence of Hodgkin's disease in spleen or lymph nodes at laparotomy is frequently impossible for the surgeon to recognize. Because of this, the routine biopsy of six abdominal nodal groups is recommended, regardless of gross appearance, in addition to splenectomy, multiple liver biopsies, and marrow biopsy. Lymphangiography has been of limited value in staging, particularly in smaller children. The unique disadvantages of radiotherapy and the unknown long-range effects of chemotherapy in the growing child make the laparotomy of greater importance in the staging of Hodgkin's disease in childhood than in the adult. |
| Databáze: | OpenAIRE |
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