Secrete or perish: The role of secretion systems in Xanthomonas biology
| Autor: | Gabriel Guarany de Araujo, Cristiane R. Guzzo, Bruno Y. Matsuyama, Maxuel O. Andrade, Cristina E. Alvarez-Martinez, Germán G. Sgro, Mateus R.N. Paiva, Chuck S. Farah |
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| Rok vydání: | 2021 |
| Předmět: |
Xanthomonas
Biophysics Virulence GENOMAS Biochemistry Genome 03 medical and health sciences Secretion systems 0302 clinical medicine Structural Biology Genetics Secretion 030304 developmental biology Whole genome sequencing 0303 health sciences biology Effector Effector proteins biology.organism_classification Computer Science Applications Bacterial adhesin 030220 oncology & carcinogenesis TP248.13-248.65 Bacteria Biotechnology |
| Zdroj: | Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 279-302 (2021) Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP |
| ISSN: | 2001-0370 |
| Popis: | Bacteria of the Xanthomonas genus are mainly phytopathogens of a large variety of crops of economic importance worldwide. Xanthomonas spp. rely on an arsenal of protein effectors, toxins and adhesins to adapt to the environment, compete with other microorganisms and colonize plant hosts, often causing disease. These protein effectors are mainly delivered to their targets by the action of bacterial secretion systems, dedicated multiprotein complexes that translocate proteins to the extracellular environment or directly into eukaryotic and prokaryotic cells. Type I to type VI secretion systems have been identified in Xanthomonas genomes. Recent studies have unravelled the diverse roles played by the distinct types of secretion systems in adaptation and virulence in xanthomonads, unveiling new aspects of their biology. In addition, genome sequence information from a wide range of Xanthomonas species and pathovars have become available recently, uncovering a heterogeneous distribution of the distinct families of secretion systems within the genus. In this review, we describe the architecture and mode of action of bacterial type I to type VI secretion systems and the distribution and functions associated with these important nanoweapons within the Xanthomonas genus. |
| Databáze: | OpenAIRE |
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