Preparation of Dental Resins Resistant to Enzymatic and Hydrolytic Degradation in Oral Environments
| Autor: | George Huyang, Rafael L. Bowen, Gili Kaufman, Abigail C. Jackson, Jirun Sun, Andres Gonzalez-Bonet, Yin Yang, Christopher Wong |
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| Rok vydání: | 2015 |
| Předmět: |
chemistry.chemical_classification
Dental composite Bisphenol A Mouth Polymers and Plastics Hydrolysis Composite number Bioengineering Ether Polymer Composite Resins Article Enzymes Biomaterials chemistry.chemical_compound Monomer chemistry Spectroscopy Fourier Transform Infrared Materials Chemistry Organic chemistry Adhesive Chromatography High Pressure Liquid |
| Zdroj: | Biomacromolecules. 16(10) |
| ISSN: | 1526-4602 |
| Popis: | The short average service life of traditional dental composite restorative materials and increasing occurrence of secondary caries adjacent to composite restorations and sealants are necessitating the development of new, longer lasting compositions. Novel monomers and their polymers, reinforcing fillers, and adhesive components are needed. The goal of this research is to develop resin systems for use in restorations, sealants, and other dental services that are superior in properties and endurance to currently used bisphenol A glycidyl dimethacrylate/triethylene glycol dimethacrylate (Bis-GMA/TEGDMA) and urethane-dimethacrylate products. Ether-based monomers and their polymers that were not susceptible to enzymatic or hydrolytic degradation were prepared and characterized. They showed no degradation under hydrolytic and enzymatic challenges, whereas the hydrolysis of ester links weakened contemporary resins within 16 days under these challenges. The success of the ether-based materials is promising in making durable systems that are subjected to long-term biochemical and hydrolytic challenges in oral environments. |
| Databáze: | OpenAIRE |
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