Doppler resistive index to reflect risk of acute kidney injury after major abdominal surgery: A prospective observational trial
| Autor: | Satyen Parida, S Deepak Barathi, Ashok Shankar Badhe, Sandeep Kumar Mishra, Kavitha Muthukrishnan |
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| Rok vydání: | 2019 |
| Předmět: |
Observational Trial
business.industry renal resistive index Doppler Acute kidney injury abdominal surgery urologic and male genital diseases medicine.disease Intensive care unit Confidence interval Resistive index law.invention lcsh:RD78.3-87.3 Anesthesiology and Pain Medicine lcsh:Anesthesiology law Anesthesia Positive predicative value medicine risk factors Original Article General anaesthesia business Abdominal surgery |
| Zdroj: | Indian Journal of Anaesthesia, Vol 63, Iss 7, Pp 551-557 (2019) Indian Journal of Anaesthesia |
| ISSN: | 0019-5049 |
| DOI: | 10.4103/ija.ija_189_19 |
| Popis: | Background and Aims: Doppler renal resistive index (RI) has been studied to find its association with postoperative acute kidney injury (AKI). This study was conducted to evaluate the usefulness of preoperative RI, postoperative RI and RI variation before and after surgery expressed as a percentage (% RI) for early AKI detection in major abdominal surgery. Methods: This was a single-centre, prospective observational trial performed in the critical care unit of an academic hospital. Eligible patients posted for major abdominal surgery under general anaesthesia using intraperitoneal approach with at least two predefined risk factors for AKI were included in the study. Renal RI was measured preoperatively and on postoperative day zero. Statistical comparisons were performed for various parameters between the AKI and the non-AKI groups. Pre- and postoperative RI receiver operating characteristics (ROC) curves were drawn and areas under the curves computed. Positive and negative predictive values, sensitivity, specificity and positive and negative likelihood ratios were calculated. Results: A total of 69 subjects were enrolled, of which 14 developed AKI in the postoperative period. The mean resistive indices measured were 0.65 ± 0.09 and 0.74 ± 0.09 in the pre- and postoperative periods, respectively. The area under the ROC curve in the postoperative RI was 0.732 with 95% confidence intervals of 0.592–0.871. This most accurate cut-off value to detect postoperative AKI with sensitivity 57.1% and specificity of 85.5% was 0.77. Conclusion: Postoperative RI can detect early AKI after major abdominal surgery. |
| Databáze: | OpenAIRE |
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