Embryo–maternal interactive factors regulating the implantation process: implications in assisted reproductive treatment
| Autor: | Serena Emiliani, Anne Delbaere, Yvon Englert, Fabienne Devreker |
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| Rok vydání: | 2005 |
| Předmět: |
medicine.medical_specialty
animal structures Reproductive Techniques Assisted Chorionic gonadotrophin Obstetrics and Gynecology Embryo Biology Bioinformatics Endometrium Blastocyst Endocrinology medicine.anatomical_structure Reproductive Medicine Pregnancy Internal medicine embryonic structures medicine Humans Female Embryo Implantation Developmental Biology Hormone |
| Zdroj: | Reproductive BioMedicine Online. 10:527-540 |
| ISSN: | 1472-6483 |
| Popis: | The embryo-maternal dialogue that starts very early in the life of the embryo is crucial for its own implantation. A disturbance in this dialogue is the major reason for which 60% of all pregnancies are terminated at the end of the periimplantation period. Many studies have been performed to improve the understanding of the molecular mechanisms involved in this dialogue. Both partners, the mother and the embryo, are equally involved in this exchange of signals. Much progress has been done in understanding the role of (i) chorionic gonadotrophin, (ii) growth factors and cytokines, and (iii) steroid hormones and other mediators, produced either by the embryo, by the mother, or by both, during the peri-implantation period. Today it is clear that their production dictates changes in the endometrium, in the immunological system of the mother and in embryo metabolism, that enable the embryo to implant. Knowledge of the molecular mechanisms involved in the embryo-maternal interaction are reviewed in this article. |
| Databáze: | OpenAIRE |
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